The Type I and II Secretory Systems in Gram-Negative Bacteria: A Brief Overview

Document Type : Review Article


1 National Institute of Genetic Engineering and Biotechnology Iran, Tehran

2 Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran


Bacteria utilize a multitude of methods to secretion of specific substrate across phospholipid membranes. These bacterial strategies can play many roles in promoting bacterial process, from enhancing pathogenesis to bacterial response to environmental condition. The secretion in bacterial species transfer and release performance substance such as proteins, enzymes and metabolites to environment. The process of secretion plays an important role in the performance and compatibility with environment. Many bacteria use dedicated protein secretion systems to secrete from the cytosol into environment. In general, bacterial protein secretion systems classified to different classes, there are at least six specific secretory systems in Gram-negative bacteria. In this study, we review type I and II secretory systems of Gram-negative bacteria.


Volume 3, Issue 3
September 2016
Pages 437-440
  • Receive Date: 15 September 2016
  • Accept Date: 15 September 2016
  • First Publish Date: 15 September 2016