Advantageous of Zebrafish (Danio rerio) in Biomedical Researches as an Animal Model: A Review

Document Type : Review Article


1 Seafood Processing Department, Marine Sciences Faculty, Tarbiat Modares University, Noor, Iran

2 Department of Aquaculture, Faculty of Natural Resources and Marine Sciences, Tarbiat Modares University, 64414-356, Noor, Iran

3 Faculty of Veterinary Medicine, University of Urmia, Urmia, Iran

4 Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

5 Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences



Different animal models including zebrafish (Danio rerio) have been widely used for several purposes in biomedical research over the past three decades. Zebrafish breed frequently and eggs develop into transparent larvae after 24 h which makes it easy to see the vital organs in real-time. It is easy to maintain and keep a large number of zebrafish in a relatively small place. The particular aim of this paper is to review the pros and cons of using zebrafish models compared to other models such as cell line, mouse, rat, etc.


Articles in Press, Accepted Manuscript
Available Online from 20 September 2022
  • Receive Date: 20 September 2022
  • Accept Date: 20 September 2022