Baqiyatallah University of Medical Sciences Journal of Applied Biotechnology Reports 2322-1186 6 2 2019 06 17 Chemical Composition and Antioxidant Activity of Solenostemma oleifolium Essential Oil from Southern Algeria 50 54 90838 10.29252/JABR.06.02.02 EN Ilyas Chikhi Laboratoire des Substances Naturelles et Bioactives (LASNABIO), Université de Tlemcen, BP 119, 13000, Algérie Centre Universitaire Belhadj Bouchaib - Ain Témouchent, Algérie Fayçal Dergal Centre de Recherche Scientifique et Technique en Analyses Physico-Chimique, C.R.A.P.C, Bp 384, Bousmail, Algérie Djazia Meryem Gana Centre Universitaire Belhadj Bouchaib - Ain Témouchent, Algérie Mohammed El Amine Dib Laboratoire des Substances Naturelles et Bioactives (LASNABIO), Université de Tlemcen, BP 119, 13000, Algérie 0000-0003-4612-5303 Hanane Chaker Centre Universitaire Belhadj Bouchaib - Ain Témouchent, Algérie Laboratoire de Catalyse et Synthèse en Chimie Organique BP 119, Université de Tlemcen, Algérie Journal Article 2019 03 23 <strong>Introduction</strong>: <em>Solenostemma oleifolium </em>is a species that grows in extremely dry conditions. It is widespread at the foot of cliffs and in rocky areas. It is a medicinal plant used for the treatment of diabetes, respiratory disorders, rheumatism, stomach pain, urinary tract infections and febrifuge. As a part of this research program on natural compounds with antioxidant properties, the main objective of this study was to determine the chemical composition and the antioxidant activity of essential oil of <em>S. oleifolium</em>.<br /> <strong>Material and Methods: </strong>In this study, the aerial parts of the plant were hydrodistilled in a Clevenger-type apparatus. The isolated essential oil was analyzed using gas chromatography mass spectrometry (GC-MS). The antioxidant activity of the essential oil was assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric-reducing power (FRAP).<br /> <strong>Results: </strong>The essential oil of <em>S. oleifolium </em>was principally characterized by oxygenated monoterpenes (94.3%) represented by linalool (59.0%), α-terpineol (14.5%) and geraniol (12.4%), followed by small amounts of nerol (3.7%) and piperitone (3.6%). The results of the antioxidant activity of essential oil showed an interesting propriety in the quenching of DPPH radical, with an IC50 of 3.3 g/L. On the other hand, essential oil showed the presence of the reductive effect, which increased with an increase in concentration.<br /> <strong>Conclusions: </strong>The results of this research showed that the <em>S. oleifolium </em>essential oil presented an interesting antioxidant property. Actually, it could be proposed as a new potential source of natural additives for the food or pharmaceutical industries. https://www.biotechrep.ir/article_90838_c7f20ee03da2557b7f3882562f0ba3de.pdf