TY - JOUR ID - 69144 TI - Growth factor Containing Hydrogels for Tissue Engineering Applications JO - Journal of Applied Biotechnology Reports JA - JABR LA - en SN - 2322-1186 AU - Babavalian, Hamid AU - Latifi, Ali Mohammad AU - Sepantafar, Mohammad Majid AU - Mohammadi, Hossein AU - Shakeri, Fatemeh AU - Khodi, Samaneh AD - Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran AD - Department of Stem Cells and Developmental Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran AD - Department of Biomaterials, Science and Research Branch, Islamic Azad University, Yazd, Iran AD - Department of biomaterials, Science and Research Branch, Islamic Azad University, Yazd, Iran Y1 - 2014 PY - 2014 VL - 1 IS - 3 SP - 83 EP - 96 DO - N2 - Regenerative medicine provides substitutes for organ transplantation, which is restricted in applicability due to immune responses against allograft and the large discrepancy between the need for organs and the number of available transplantation. An artificial environment is allowing cells to induce tissue regeneration. Growth factors (GFs) play a significant role in the cell fates in their microenvironment. Nevertheless, the short half-lives of GFs and poor in vivo stability infiltration suggest that the classical routes are useless and insist on use of a drug delivery system (DDS). In this review paper, growth factor-based tissue regeneration using polymeric hydrogels is reviewed to show great potential ability of hydrogels in tissue engineering (TE). UR - https://www.biotechrep.ir/article_69144.html L1 - https://www.biotechrep.ir/article_69144_552039da2be13115f3af42c9e2a99ab9.pdf ER -